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Fanconi Anemia Proteins, DNA Interstrand Crosslink Repair Pathways, and Cancer Therapy

DNA interstrand crosslinkers, a chemically diverse group of compounds which also induce alkylation of bases and DNA intrastrand crosslinks, are extensively utilized for cancer therapy. Understanding the cellular response to DNA damage induced by these agents is critical for more effective utilizatio...

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Detalhes bibliográficos
Publicado no:Curr Cancer Drug Targets
Main Authors: Andreassen, Paul R., Ren, Keqin
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934657/
https://ncbi.nlm.nih.gov/pubmed/19200054
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