Deoxycholic acid (DCA) confers an intestinal phenotype on esophageal squamous epithelium via induction of the stemness-associated reprogramming factors OCT4 and SOX2

Barrett's esophagus (BE) is essentially a metaplasia in which the normal stratified squamous epithelium is replaced by columnar epithelium. This study focuses on the involvement of OCT4 and SOX2, 2 key cell-reprogramming factors, in the deoxycholic acid (DCA)-induced expression of the intestina...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Shen, Caifei, Zhang, Haoxiang, Wang, Pu, Feng, Ji, Li, Jingwen, Xu, Yin, Zhang, Anran, Shao, Shunzi, Yu, Xiaona, Yan, Wu, Xia, Yiju, Hu, Jiali, Fang, Dianchun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934056/
https://ncbi.nlm.nih.gov/pubmed/27096226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1175252
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