Heterokaryon-Based Reprogramming of Human B Lymphocytes for Pluripotency Requires Oct4 but Not Sox2

Differentiated cells can be reprogrammed through the formation of heterokaryons and hybrid cells when fused with embryonic stem (ES) cells. Here, we provide evidence that conversion of human B-lymphocytes towards a multipotent state is initiated much more rapidly than previously thought, occurring i...

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Autori principali: Pereira, Carlos F., Terranova, Rémi, Ryan, Natalie K., Santos, Joana, Morris, Kelly J., Cui, Wei, Merkenschlager, Matthias, Fisher, Amanda G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527997/
https://ncbi.nlm.nih.gov/pubmed/18773085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000170
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