MET Inhibition in Clear Cell Renal Cell Carcinoma

Background: Clear cell renal cell carcinoma (ccRCC) is the most lethal form of kidney cancer. Small molecule VEGFR inhibitors are widely used but are not curative and various resistance mechanisms such as activation of the MET pathway have been described. Dual MET/VEGFR2 inhibitors have recently sho...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Xie, Zuoquan, Lee, Young H., Boeke, Marta, Jilaveanu, Lucia B., Liu, Zongzhi, Bottaro, Donald P., Kluger, Harriet M., Shuch, Brian
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934028/
https://ncbi.nlm.nih.gov/pubmed/27390595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.14604
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