MET Inhibition in Clear Cell Renal Cell Carcinoma

Background: Clear cell renal cell carcinoma (ccRCC) is the most lethal form of kidney cancer. Small molecule VEGFR inhibitors are widely used but are not curative and various resistance mechanisms such as activation of the MET pathway have been described. Dual MET/VEGFR2 inhibitors have recently sho...

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Vydáno v:J Cancer
Hlavní autoři: Xie, Zuoquan, Lee, Young H., Boeke, Marta, Jilaveanu, Lucia B., Liu, Zongzhi, Bottaro, Donald P., Kluger, Harriet M., Shuch, Brian
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934028/
https://ncbi.nlm.nih.gov/pubmed/27390595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.14604
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