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Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylome
BACKGROUND: Transmission fidelity of CpG DNA methylation patterns is not foolproof, with error rates from less than 1 to well over 10 % per CpG site, dependent on preservation of the methylated or unmethylated state and the type of sequence. This suggests a fairly high chance of errors. However, the...
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| Publicat a: | Genome Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934005/ https://ncbi.nlm.nih.gov/pubmed/27380908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1011-3 |
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