Genome-wide, Single-Cell DNA Methylomics Reveals Increased Non-CpG Methylation during Human Oocyte Maturation

The establishment of DNA methylation patterns in oocytes is a highly dynamic process marking gene-regulatory events during fertilization, embryonic development, and adulthood. However, after epigenetic reprogramming in primordial germ cells, how and when DNA methylation is re-established in developi...

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Gepubliceerd in:Stem Cell Reports
Hoofdauteurs: Yu, Bo, Dong, Xiao, Gravina, Silvia, Kartal, Önder, Schimmel, Timothy, Cohen, Jacques, Tortoriello, Drew, Zody, Raifa, Hawkins, R. David, Vijg, Jan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511109/
https://ncbi.nlm.nih.gov/pubmed/28648898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.026
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