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Genome-wide analysis of DNA methylation during antagonism of DMOG to MnCl2-induced cytotoxicity in the mouse substantia nigra

Exposure to excessive manganese (Mn) causes manganism, a progressive neurodegenerative disorder similar to idiopathic Parkinson’s disease (IPD). The detailed mechanisms of Mn neurotoxicity in nerve cells, especially in dopaminergic neurons are not yet fully understood. Meanwhile, it is unknown wheth...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Nannan, Wei, Yang, Wang, Tan, Guo, Jifeng, Sun, Qiying, Hu, Yacen, Yan, Xinxiang, Zhu, Xiongwei, Tang, Beisha, Xu, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933877/
https://ncbi.nlm.nih.gov/pubmed/27380887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28933
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