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Condensation of supercoiled DNA induced by MnCl2.

Multivalent cations condense DNA in vitro, but it had been thought that a valence of at least + 3 was required in aqueous solution. We have found that Mn2+ can produce toroidal condensates of supercoiled plasmid DNA, but not of linearized plasmid. Mg2+ does not cause condensation, and neither MgCl2...

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Detalhes bibliográficos
Main Authors: Ma, C, Bloomfield, V A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1225529/
https://ncbi.nlm.nih.gov/pubmed/7819499
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