Genome-wide analysis of DNA methylation during antagonism of DMOG to MnCl2-induced cytotoxicity in the mouse substantia nigra

Exposure to excessive manganese (Mn) causes manganism, a progressive neurodegenerative disorder similar to idiopathic Parkinson’s disease (IPD). The detailed mechanisms of Mn neurotoxicity in nerve cells, especially in dopaminergic neurons are not yet fully understood. Meanwhile, it is unknown wheth...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Yang, Nannan, Wei, Yang, Wang, Tan, Guo, Jifeng, Sun, Qiying, Hu, Yacen, Yan, Xinxiang, Zhu, Xiongwei, Tang, Beisha, Xu, Qian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933877/
https://ncbi.nlm.nih.gov/pubmed/27380887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28933
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