Genome-wide analysis of DNA methylation during antagonism of DMOG to MnCl2-induced cytotoxicity in the mouse substantia nigra

Exposure to excessive manganese (Mn) causes manganism, a progressive neurodegenerative disorder similar to idiopathic Parkinson’s disease (IPD). The detailed mechanisms of Mn neurotoxicity in nerve cells, especially in dopaminergic neurons are not yet fully understood. Meanwhile, it is unknown wheth...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yang, Nannan, Wei, Yang, Wang, Tan, Guo, Jifeng, Sun, Qiying, Hu, Yacen, Yan, Xinxiang, Zhu, Xiongwei, Tang, Beisha, Xu, Qian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933877/
https://ncbi.nlm.nih.gov/pubmed/27380887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28933
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