An HIV gp120-CD4 Immunogen Does Not Elicit Autoimmune Antibody Responses in Cynomolgus Macaques

A promising concept for human immunodeficiency virus (HIV) vaccines focuses immunity on the highly conserved transition state structures and epitopes that appear when the HIV glycoprotein gp120 binds to its receptor, CD4. We are developing chimeric antigens (full-length single chain, or FLSC) in whi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Vaccine Immunol
Main Authors: Schwartz, Jennifer A., Prado, Ilia, Misamore, Johnathan, Weiss, Deborah, Francis, Jesse, Pal, Ranajit, Huaman, Maria, Cristillo, Anthony, Lewis, George K., Gallo, Robert C., DeVico, Anthony L., Fouts, Timothy R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933776/
https://ncbi.nlm.nih.gov/pubmed/27193040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00115-16
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