Identification and Characterization of an Immunogenic Hybrid Epitope Formed by both HIV gp120 and Human CD4 Proteins

Certain antibodies from HIV-infected humans bind conserved transition state (CD4 induced [CD4i]) domains on the HIV envelope glycoprotein, gp120, and demonstrate extreme dependence on the formation of a gp120-human CD4 receptor complex. The epitopes recognized by these antibodies remain undefined al...

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Detalhes bibliográficos
Main Authors: Lewis, George K., Fouts, Timothy R., Ibrahim, Sani, Taylor, Brian M., Salkar, Rachita, Guan, Yongjun, Kamin-Lewis, Roberta, DeVico, Anthony L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233132/
https://ncbi.nlm.nih.gov/pubmed/21994452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05072-11
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