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Antibodies to CD4-induced sites in HIV gp120 correlate with the control of SHIV challenge in macaques vaccinated with subunit immunogens

Epitopes located in and around the coreceptor binding site of HIV-1 envelope glycoprotein (gp120) exhibit enhanced exposure after attachment to the CD4 receptor and comprise some of the most conserved and functionally important residues on the viral envelope. Therefore, antibody responses to these e...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: DeVico, Anthony, Fouts, Timothy, Lewis, George K., Gallo, Robert C., Godfrey, Karla, Charurat, Manhattan, Harris, Ilia, Galmin, Lindsey, Pal, Ranajit
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077281/
https://ncbi.nlm.nih.gov/pubmed/17956985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707399104
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