Acute systemic DNA damage in youth does not impair immune defense with aging

Aging‐related decline in immunity is believed to be the main driver behind decreased vaccine efficacy and reduced resistance to infections in older adults. Unrepaired DNA damage is known to precipitate cellular senescence, which was hypothesized to be the underlying cause of certain age‐related phen...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging Cell
Päätekijät: Pugh, Jason L., Foster, Sarah A., Sukhina, Alona S., Petravic, Janka, Uhrlaub, Jennifer L., Padilla‐Torres, Jose, Hayashi, Tomonori, Nakachi, Kei, Smithey, Megan J., Nikolich‐Žugich, Janko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933672/
https://ncbi.nlm.nih.gov/pubmed/27072188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12478
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