Acute systemic DNA damage in youth does not impair immune defense with aging

Aging‐related decline in immunity is believed to be the main driver behind decreased vaccine efficacy and reduced resistance to infections in older adults. Unrepaired DNA damage is known to precipitate cellular senescence, which was hypothesized to be the underlying cause of certain age‐related phen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Pugh, Jason L., Foster, Sarah A., Sukhina, Alona S., Petravic, Janka, Uhrlaub, Jennifer L., Padilla‐Torres, Jose, Hayashi, Tomonori, Nakachi, Kei, Smithey, Megan J., Nikolich‐Žugich, Janko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933672/
https://ncbi.nlm.nih.gov/pubmed/27072188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12478
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