Acute systemic DNA damage in youth does not impair immune defense with aging

Aging‐related decline in immunity is believed to be the main driver behind decreased vaccine efficacy and reduced resistance to infections in older adults. Unrepaired DNA damage is known to precipitate cellular senescence, which was hypothesized to be the underlying cause of certain age‐related phen...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Pugh, Jason L., Foster, Sarah A., Sukhina, Alona S., Petravic, Janka, Uhrlaub, Jennifer L., Padilla‐Torres, Jose, Hayashi, Tomonori, Nakachi, Kei, Smithey, Megan J., Nikolich‐Žugich, Janko
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933672/
https://ncbi.nlm.nih.gov/pubmed/27072188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12478
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