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Fluoxetine synergizes with temozolomide to induce the CHOP-dependent endoplasmic reticulum stress-related apoptosis pathway in glioma cells

Although temozolomide (TMZ) is the most effective chemotherapy agent for glioma, chemotherapy resistance has limited its clinical use. Fluoxetine (FLT), which is widely used in cancer-related depression, has exhibited potent anticancer properties in different cancer cell types. The aim of this study...

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Publicado en:Oncol Rep
Autores principales: Ma, Jian, Yang, Yan-Ru, Chen, Wei, Chen, Mei-Hua, Wang, Hao, Wang, Xiao-Dan, Sun, Li-Li, Wang, Feng-Ze, Wang, De-Cai
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933544/
https://ncbi.nlm.nih.gov/pubmed/27278525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4860
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