Inhibition of Mitochondria- and Endoplasmic Reticulum Stress-Mediated Autophagy Augments Temozolomide-Induced Apoptosis in Glioma Cells

Autophagy is a crucial process for cells to maintain homeostasis and survival through degradation of cellular proteins and organelles, including mitochondria and endoplasmic reticula (ER). We previously demonstrated that temozolomide (TMZ), an alkylating agent for brain tumor chemotherapy, induced r...

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Bibliografski detalji
Glavni autori: Lin, Chien-Ju, Lee, Chin-Cheng, Shih, Yung-Luen, Lin, Chien-Huang, Wang, Sheng-Hao, Chen, Thay-Hsiung, Shih, Chwen-Ming
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382156/
https://ncbi.nlm.nih.gov/pubmed/22745676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038706
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