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Inhibition of Mitochondria- and Endoplasmic Reticulum Stress-Mediated Autophagy Augments Temozolomide-Induced Apoptosis in Glioma Cells

Autophagy is a crucial process for cells to maintain homeostasis and survival through degradation of cellular proteins and organelles, including mitochondria and endoplasmic reticula (ER). We previously demonstrated that temozolomide (TMZ), an alkylating agent for brain tumor chemotherapy, induced r...

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מידע ביבליוגרפי
Main Authors: Lin, Chien-Ju, Lee, Chin-Cheng, Shih, Yung-Luen, Lin, Chien-Huang, Wang, Sheng-Hao, Chen, Thay-Hsiung, Shih, Chwen-Ming
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382156/
https://ncbi.nlm.nih.gov/pubmed/22745676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038706
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