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Solid-state Characterization of Felodipine-Soluplus(®) Amorphous Solid Dispersions
The aim of the current study is to develop amorphous solid dispersion via hot melt extrusion technology to improve the solubility of a water-insoluble compound, felodipine. The solubility was dramatically increased by preparation of amorphous solid dispersions via hot-melt extrusion with an amphiphi...
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Publicado no: | Drug Dev Ind Pharm |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933522/ https://ncbi.nlm.nih.gov/pubmed/26530290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03639045.2015.1104347 |
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