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A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins

A quality control system in the endoplasmic reticulum (ER) efficiently discriminates polypeptides that are in the process of productive folding from conformers that are trapped in an aberrant state. Only the latter are transported into the cytoplasm and degraded in a process termed ER-associated pro...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pfeiffer, Anett, Stephanowitz, Heike, Krause, Eberhard, Volkwein, Corinna, Hirsch, Christian, Jarosch, Ernst, Sommer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933269/
https://ncbi.nlm.nih.gov/pubmed/27053108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.703256
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