γ-Aminobutyric Acid Type A (GABA(A)) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains

The establishment of cell-cell contacts between presynaptic GABAergic neurons and their postsynaptic targets initiates the process of GABAergic synapse formation. GABA(A) receptors (GABA(A)Rs), the main postsynaptic receptors for GABA, have been recently demonstrated to act as synaptogenic proteins...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Brown, Laura E., Nicholson, Martin W., Arama, Jessica E., Mercer, Audrey, Thomson, Alex M., Jovanovic, Jasmina N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933154/
https://ncbi.nlm.nih.gov/pubmed/27129275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.714790
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