γ-Aminobutyric Acid Type A (GABA(A)) Receptor α Subunits Play a Direct Role in Synaptic Versus Extrasynaptic Targeting

GABA(A) receptors (GABA(A)-Rs) are localized at both synaptic and extrasynaptic sites, mediating phasic and tonic inhibition, respectively. Previous studies suggest an important role of γ2 and δ subunits in synaptic versus extrasynaptic targeting of GABA(A)-Rs. Here, we demonstrate differential func...

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Detalhes bibliográficos
Main Authors: Wu, Xia, Wu, Zheng, Ning, Gang, Guo, Yao, Ali, Rashid, Macdonald, Robert L., De Blas, Angel L., Luscher, Bernhard, Chen, Gong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431651/
https://ncbi.nlm.nih.gov/pubmed/22711532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.360461
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