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CD28 costimulation: from mechanism to therapy
Ligation of the CD28 receptor on T cells provides a critical second signal alongside T cell receptor (TCR) ligation for naive T cell activation. Here we discuss the expression, structure, and biochemistry of CD28 and its ligands. CD28 signals play a key role in many T cell processes including cytosk...
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| Veröffentlicht in: | Immunity |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932896/ https://ncbi.nlm.nih.gov/pubmed/27192564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.04.020 |
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