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CD28 costimulation: from mechanism to therapy

Ligation of the CD28 receptor on T cells provides a critical second signal alongside T cell receptor (TCR) ligation for naive T cell activation. Here we discuss the expression, structure, and biochemistry of CD28 and its ligands. CD28 signals play a key role in many T cell processes including cytosk...

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Bibliografski detalji
Izdano u:Immunity
Glavni autori: Esensten, Jonathan H., Helou, Ynes A., Chopra, Gaurav, Weiss, Arthur, Bluestone, Jeffrey A.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932896/
https://ncbi.nlm.nih.gov/pubmed/27192564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.04.020
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