CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation.

T-cell activation involves two distinct signal transduction pathways. Antigen-specific signaling events are initiated by T-cell receptor recognition of cognate peptide presented by major histocompatibility complex molecules. Costimulatory signals, which are required for optimal T-cell activation and...

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Bibliographische Detailangaben
Hauptverfasser: Crooks, M E, Littman, D R, Carter, R H, Fearon, D T, Weiss, A, Stein, P H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC230936/
https://ncbi.nlm.nih.gov/pubmed/8524248
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