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Transnasal delivery of human A-beta peptides elicits impaired learning and memory performance in wild type mice
BACKGROUND: Murine models of Alzheimer’s disease (AD) are mainly based on overexpression of pathologic amyloid precursor protein and/or presenilins. Those genes resemble underlying cause of early onset type of AD while about 99 % of all human cases are to be characterized as sporadic, late onset. Ap...
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| Publicado no: | BMC Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932715/ https://ncbi.nlm.nih.gov/pubmed/27377996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0280-9 |
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