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Identification of trichlormethiazide as a Mdr1a/b gene expression enhancer via a dual secretion-based promoter assay
Transporters of the ATP-binding cassette (ABC) family such as MDR1 play a pivotal role in persistence of brain homeostasis by contributing to the strict permeability properties of the blood–brain barrier. This barrier on one hand compromises treatment of central nervous system diseases by restrictin...
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| Udgivet i: | Pharmacol Res Perspect |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317239/ https://ncbi.nlm.nih.gov/pubmed/25692026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.109 |
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