Expressing Constitutively Active Rheb in Adult Dorsal Root Ganglion Neurons Enhances the Integration of Sensory Axons that Regenerate Across a Chondroitinase-Treated Dorsal Root Entry Zone Following Dorsal Root Crush

While the peripheral branch of dorsal root ganglion neurons (DRG) can successfully regenerate after injury, lesioned central branch axons fail to regrow across the dorsal root entry zone (DREZ), the interface between the dorsal root and the spinal cord. This lack of regeneration is due to the limite...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Wu, Di, Klaw, Michelle C., Kholodilov, Nikolai, Burke, Robert E., Detloff, Megan R., Côté, Marie-Pascale, Tom, Veronica J.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4932115/
https://ncbi.nlm.nih.gov/pubmed/27458339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00049
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