Combining Constitutively Active Rheb Expression and Chondroitinase Promotes Functional Axonal Regeneration after Cervical Spinal Cord Injury

After spinal cord injury (SCI), severed axons in the adult mammalian CNS are unable to mount a robust regenerative response. In addition, the glial scar at the lesion site further restricts the regenerative potential of axons. We hypothesized that a combinatorial approach coincidentally targeting th...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Ther
Hlavní autoři: Wu, Di, Klaw, Michelle C., Connors, Theresa, Kholodilov, Nikolai, Burke, Robert E., Côté, Marie-Pascale, Tom, Veronica J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5768590/
https://ncbi.nlm.nih.gov/pubmed/28967557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.08.011
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky