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Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity
Salicylate and acetylsalicylic acid are potent and widely used anti-inflammatory drugs. They are thought to exert their therapeutic effects through multiple mechanisms, including the inhibition of cyclo-oxygenases, modulation of NF-κB activity, and direct activation of AMPK. However, the full spectr...
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| Wydane w: | eLife |
|---|---|
| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
eLife Sciences Publications, Ltd
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931907/ https://ncbi.nlm.nih.gov/pubmed/27244239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11156 |
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