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SIRT6 protects against endothelial dysfunction and atherosclerosis in mice
SIRT6 is an important member of sirtuin family that represses inflammation, aging and DNA damage, three of which are causing factors for endothelial dysfunction. SIRT6 expression is decreased in atherosclerotic lesions from ApoE(−/−) mice and human patients. However, the role of SIRT6 in regulating...
Gardado en:
| Publicado en: | Aging (Albany NY) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931854/ https://ncbi.nlm.nih.gov/pubmed/27249230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100975 |
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