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Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures

Aging is reflected by highly reproducible DNA methylation (DNAm) changes that open new perspectives for estimation of chronological age in legal medicine. DNA can be harvested non-invasively from cells at the inside of a person's cheek using buccal swabs – but these specimens resemble heterogen...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Eipel, Monika, Mayer, Felix, Arent, Tanja, Ferreira, Marcelo R. P., Birkhofer, Carina, Gerstenmaier, Uwe, Costa, Ivan G., Ritz-Timme, Stefanie, Wagner, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931852/
https://ncbi.nlm.nih.gov/pubmed/27249102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100972
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