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Epigenetic Aging Signatures Are Coherently Modified in Cancer

Aging is associated with highly reproducible DNA methylation (DNAm) changes, which may contribute to higher prevalence of malignant diseases in the elderly. In this study, we analyzed epigenetic aging signatures in 5,621 DNAm profiles of 25 cancer types from The Cancer Genome Atlas (TCGA). Overall,...

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書誌詳細
出版年:PLoS Genet
主要な著者: Lin, Qiong, Wagner, Wolfgang
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482318/
https://ncbi.nlm.nih.gov/pubmed/26110659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005334
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