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Epigenetic Aging Signatures Are Coherently Modified in Cancer

Aging is associated with highly reproducible DNA methylation (DNAm) changes, which may contribute to higher prevalence of malignant diseases in the elderly. In this study, we analyzed epigenetic aging signatures in 5,621 DNAm profiles of 25 cancer types from The Cancer Genome Atlas (TCGA). Overall,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Genet
Egile Nagusiak: Lin, Qiong, Wagner, Wolfgang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482318/
https://ncbi.nlm.nih.gov/pubmed/26110659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005334
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