IVIg attenuates complement and improves spinal cord injury outcomes in mice

OBJECTIVE: Traumatic spinal cord injury (SCI) elicits immediate neural cell death, axonal damage, and disruption of the blood–spinal cord barrier, allowing circulating immune cells and blood proteins into the spinal parenchyma. The inflammatory response to SCI involves robust complement system activ...

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Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Brennan, Faith H., Kurniawan, Nyoman D., Vukovic, Jana, Bartlett, Perry F., Käsermann, Fabian, Arumugam, Thiruma V., Basta, Milan, Ruitenberg, Marc J.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931715/
https://ncbi.nlm.nih.gov/pubmed/27386499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.318
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