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In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study

Light chain (AL) amyloidosis, caused by deposition of amyloidogenic immunoglobulin light chains (LCs), is the most common systemic form in industrialized countries. Still open questions, and premises for developing targeted therapies, concern the mechanisms of amyloid formation in vivo and the bases...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Ami, Diletta, Lavatelli, Francesca, Rognoni, Paola, Palladini, Giovanni, Raimondi, Sara, Giorgetti, Sofia, Monti, Luca, Doglia, Silvia Maria, Natalello, Antonino, Merlini, Giampaolo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931462/
https://ncbi.nlm.nih.gov/pubmed/27373200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29096
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