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LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development

The Hippo pathway regulates the self-renewal and differentiation of various adult stem cells, but its role in cell fate determination and differentiation during liver development remains unclear. Here we report that the Hippo pathway controls liver cell lineage specification and proliferation separa...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Lee, Da-Hye, Park, Jae Oh, Kim, Tae-Shin, Kim, Sang-Kyum, Kim, Tack-hoon, Kim, Min-chul, Park, Gun Soo, Kim, Jeong-Hwan, Kuninaka, Shinji, Olson, Eric N., Saya, Hideyuki, Kim, Seon-Young, Lee, Ho, Lim, Dae-Sik
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931324/
https://ncbi.nlm.nih.gov/pubmed/27358050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11961
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