LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development

The Hippo pathway regulates the self-renewal and differentiation of various adult stem cells, but its role in cell fate determination and differentiation during liver development remains unclear. Here we report that the Hippo pathway controls liver cell lineage specification and proliferation separa...

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Udgivet i:Nat Commun
Main Authors: Lee, Da-Hye, Park, Jae Oh, Kim, Tae-Shin, Kim, Sang-Kyum, Kim, Tack-hoon, Kim, Min-chul, Park, Gun Soo, Kim, Jeong-Hwan, Kuninaka, Shinji, Olson, Eric N., Saya, Hideyuki, Kim, Seon-Young, Lee, Ho, Lim, Dae-Sik
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931324/
https://ncbi.nlm.nih.gov/pubmed/27358050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11961
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