TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype

The heterogeneous nature of colorectal cancer (CRC) complicates prognosis and is suggested to be a determining factor in the efficacy of adjuvant therapy for individual patients. Based on gene expression profiling, CRC is currently classified into four consensus molecular subtypes (CMSs), characteri...

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Publicado en:EMBO Mol Med
Autores principales: Fessler, Evelyn, Drost, Jarno, van Hooff, Sander R, Linnekamp, Janneke F, Wang, Xin, Jansen, Marnix, De Sousa E Melo, Felipe, Prasetyanti, Pramudita R, IJspeert, Joep EG, Franitza, Marek, Nürnberg, Peter, van Noesel, Carel JM, Dekker, Evelien, Vermeulen, Louis, Clevers, Hans, Medema, Jan Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931289/
https://ncbi.nlm.nih.gov/pubmed/27221051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201606184
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