A Serrated Colorectal Cancer Pathway Predominates over the Classic WNT Pathway in Patients with Hyperplastic Polyposis Syndrome

Hyperplastic polyposis syndrome (HPS) is characterized by the presence of multiple colorectal serrated polyps and is associated with an increased colorectal cancer (CRC) risk. The mixture of distinct precursor lesion types and malignancies in HPS provides a unique model to study the canonical pathwa...

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Detalhes bibliográficos
Main Authors: Boparai, Karam S., Dekker, Evelien, Polak, Mirjam M., Musler, Alex R., van Eeden, Susanne, van Noesel, Carel J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124356/
https://ncbi.nlm.nih.gov/pubmed/21641392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.02.023
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