A Serrated Colorectal Cancer Pathway Predominates over the Classic WNT Pathway in Patients with Hyperplastic Polyposis Syndrome

Hyperplastic polyposis syndrome (HPS) is characterized by the presence of multiple colorectal serrated polyps and is associated with an increased colorectal cancer (CRC) risk. The mixture of distinct precursor lesion types and malignancies in HPS provides a unique model to study the canonical pathwa...

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Bibliografische gegevens
Hoofdauteurs: Boparai, Karam S., Dekker, Evelien, Polak, Mirjam M., Musler, Alex R., van Eeden, Susanne, van Noesel, Carel J.M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2011
Onderwerpen:
Regular Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3124356/
https://ncbi.nlm.nih.gov/pubmed/21641392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.02.023
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