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A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2

Pancreatic cancers with aberrant expression of macrophage migration inhibitory factor (MIF) are particularly aggressive. To identify key signaling pathways that drive disease aggressiveness in tumors with high MIF expression, we analyzed the expression of coding and non-coding genes in high and low...

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Bibliografiske detaljer
Udgivet i:Cancer Res
Main Authors: Yang, Shouhui, He, Peijun, Wang, Jian, Schetter, Aaron, Tang, Wei, Funamizu, Naotake, Yanaga, Katsuhiko, Uwagawa, Tadashi, Satoskar, Abhay R., Gaedcke, Jochen, Bernhardt, Markus, Ghadimi, B. Michael, Gaida, Matthias M., Bergmann, Frank, Werner, Jens, Ried, Thomas, Hanna, Nader, Alexander, H. Richard, Hussain, S. Perwez
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930741/
https://ncbi.nlm.nih.gov/pubmed/27197190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-2841
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