Androgen deprivation followed by acute androgen stimulation selectively sensitizes AR-positive prostate cancer cells to ionizing radiation

PURPOSE: The current standard of care for patients with locally advanced prostate cancer is a combination of androgen deprivation and radiation therapy. Radiation is typically given with androgen suppression when testosterone levels are at their nadir. Recent reports have shown that androgen stimula...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Hedayati, Mohammad, Haffner, Michael C., Coulter, Jonathan B., Raval, Raju R., Zhang, Yonggang, Zhou, Haoming, Mian, Omar, Knight, Emma J., Razavi, Nina, Dalrymple, Susan, Isaacs, John T., Santos, Aileen, Hales, Russell, Nelson, William G., Yegnasubramanian, Srinivasan, DeWeese, Theodore L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930695/
https://ncbi.nlm.nih.gov/pubmed/26831716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1147
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge