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Tasquinimod Prevents the Angiogenic Rebound Induced by Fractionated Radiation Resulting in an Enhanced Therapeutic Response of Prostate Cancer Xenografts

BACKGROUND: Tasquinimod is a novel inhibitor of tumor angiogenesis which enhances therapeutic efficacy when combined with androgen ablation and/or taxane-based chemotherapies in pre-clinical prostate cancer models. It has entered registration Phase III evaluation for the treatment of castration resi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dalrymple, Susan L., Becker, Robyn E., Zhou, Haoming, DeWeese, Theodore L., Isaacs, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086682/
https://ncbi.nlm.nih.gov/pubmed/21837778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21467
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