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Burden of non-synonymous mutations among TCGA cancers and candidate immune checkpoint inhibitor responses

Immune checkpoint inhibitor treatment represents a promising approach towards treating cancer and has been shown to be effective in a subset of melanoma, non-small cell lung cancer (NSCLC) and kidney cancers. Recent studies have suggested that the number of non-synonymous mutations (NsM) can be used...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Colli, Leandro M., Machiela, Mitchell J., Myers, Timothy, Jessop, Lea, Yu, Kai, Chanock, Stephen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930685/
https://ncbi.nlm.nih.gov/pubmed/27197178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0170
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