Functional characterization of the 12p12.1 renal cancer-susceptibility locus implicates BHLHE41

Genome-wide association studies have identified multiple renal cell carcinoma (RCC) susceptibility loci. Here, we use regional imputation and bioinformatics analysis of the 12p12.1 locus to identify the single-nucleotide polymorphism (SNP) rs7132434 as a potential functional variant. Luciferase assa...

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發表在:Nat Commun
Main Authors: Bigot, Pierre, Colli, Leandro M., Machiela, Mitchell J., Jessop, Lea, Myers, Timothy A., Carrouget, Julie, Wagner, Sarah, Roberson, David, Eymerit, Caroline, Henrion, Daniel, Chanock, Stephen J.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941055/
https://ncbi.nlm.nih.gov/pubmed/27384883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12098
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