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Investigation of allosteric coupling in human β(2)-adrenergic receptor in the presence of intracellular loop 3

BACKGROUND: This study investigates the allosteric coupling that exists between the intra- and extracellular parts of human β(2)-adrenergic receptor (β(2)-AR), in the presence of the intracellular loop 3 (ICL3), which is missing in all crystallographic experiments and most of the simulation studies...

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發表在:BMC Struct Biol
Main Authors: Ozgur, Canan, Doruker, Pemra, Akten, E. Demet
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930610/
https://ncbi.nlm.nih.gov/pubmed/27368374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0061-9
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