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Mechanism of allosteric regulation of β(2)-adrenergic receptor by cholesterol

There is evidence that lipids can be allosteric regulators of membrane protein structure and activation. However, there are no data showing how exactly the regulation emerges from specific lipid-protein interactions. Here we show in atomistic detail how the human β(2)-adrenergic receptor (β(2)AR) –...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Manna, Moutusi, Niemelä, Miia, Tynkkynen, Joona, Javanainen, Matti, Kulig, Waldemar, Müller, Daniel J, Rog, Tomasz, Vattulainen, Ilpo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182060/
https://ncbi.nlm.nih.gov/pubmed/27897972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18432
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