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Effect of intracellular loop 3 on intrinsic dynamics of human β(2)-adrenergic receptor

BACKGROUND: To understand the effect of the long intracellular loop 3 (ICL3) on the intrinsic dynamics of human β(2)-adrenergic receptor, molecular dynamics (MD) simulations were performed on two different models, both of which were based on the inactive crystal structure in complex with carazolol (...

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Detalles Bibliográficos
Main Authors: Ozcan, Ozer, Uyar, Arzu, Doruker, Pemra, Akten, Ebru Demet
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834532/
https://ncbi.nlm.nih.gov/pubmed/24206668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-29
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